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神経炎症に関する研究

  1. Tachibana M et al. Clasmatodendrosis is associated with dendritic spines and does not represent autophagic astrocyte death in influenza-associated encephalopathy. Brain Dev. 2019 Jan;41(1):85-95. doi: 10.1016/j.braindev.2018.07.008.
  2. Redensek A et al. Expression and Detrimental Role of Hematopoietic Prostaglandin D Synthase in Spinal Cord Contusion Injury. Glia. 2011 Apr;59(4):603-14. doi: 10.1002/glia.21128.
  3. Araya K et al. Localized donor cells in brain of a Hunter disease patient after cord blood stem cell transplantation. Mol Genet Metab. 2009. 98(3):255-63. doi: 10.1016/j.ymgme.2009.05.006.
  4. Mohri I et al. Inhibition of prostaglandin D synthase suppresses muscular necrosis. Am J Pathol. 2009 May; 174(5):1735-44. doi: 10.2353/ajpath.2009.080709. Epub 2009 Apr 9.
  5. Hematopoietic prostaglandin D synthase and DP1 receptor are selectively upregulated in microglia and astrocytes within senile plaques from human patients and in a mouse model of Alzheimer disease. J Neuropathol Exp Neurol. 66(6):469-80.2007.
  6. Taniguchi H et al. Early induction of neuronal lipocalin-type prostaglandin D synthase after hypoxic-ischemic injury in developing brains. Neurosci Lett. Jun 8;420(1):39-44. 2007.
  7. Taniguchi H et al. Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic injury. J Neurosci. Apr 18;27(16):4303-12.2007.
  8. Kanekiyo T et al. Lipocalin-type prostaglandin D synthase/beta-trace is a major amyloid beta-chaperone in human cerebrospinal fluid. Proc Natl Acad Sci U S A.;104(15):6412-7. Epub 2007 Apr 2.
  9. Urade Y and Mohri I. Sleep and brain function. No To Hattatsu. (2006) Sep;38(5):331-3.
  10. Langmade SJ et al. Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease. (2006) Proc Natl Acad Sci U S A. Sep 12;103(37):13807-12. Epub 2006 Aug 29.
  11. A de novo deafwaddler mutation of Pmca2 arising in ES cells and hitchhiking with a targeted modification of the PPARg gene. Mamm Genome. Jul;17(7):716-22.2006
  12. Mohri I et al. Prostaglandin D2-mediated Microglia/Astrocyte Interaction Enhances Astrogliosis and Demyelination in Twitcher. J Neurosci 26(16):4383-93. 2006.
  13. Lipocalin-type Prostaglandin D Synthase Is Upregulated in Oligodendrocytes in Lysosomal Storage Diseases and Binds Gangliosides. J Neurochem 97(3):641-51.2006.
  14. Kagitani-Shimono K et al. Lipocalin-type Prostaglandin D Synthase (b-trace) is Upregulated in the aB-crystallin-positive oligodendrocytes and astrocytes in the chronic Multiple Sclerosis. Neuropath Appl Neurobiol 32:64-73. 2006
  15. Kagitani-Shimono K et al. Anti-inflammatory therapy by ibudilast, a phosphodiesterase inhibitor, in demyelination of twitcher, a genetic demyelination model. J Neuroinflammation. 2:10. 2005
  16. Yagi T et al. Comparative clinico-pathological study of saposin-A-deficient (SAP-A-/-) and Twitcher mice. J Neuropathol Exp Neurol. 63:721-34. 2004.
  17. Takikita S et al. Perturbed myelination process of premyelinating oligodendrocyte in Niemann-Pick type C mouse. J Neuropathol Exp Neurol. 2004 63:660-73. 2004.
  18. Yagi T et al. Fate of donor hematopoietic cells in demyelinating mutant mouse, twitcher, following transplantation of GFP+ bone marrow cells. Neurobiol Dis. 16:98-109. 2004.
  19. Hematopoietic prostaglandin D synthase is expressed in microglia in the developing postnatal mouse brain. Glia, 42(3): 263-274. 2003.
  20. Taniike M et al. Perineuronal oligodendrocytes protect against neuronal apoptosis through the production of lipocalin-type prostaglandin D synthase in a genetic demyelinating model. J Neurosci 22: 4885-4896. 2002)*: Equally contributed
  21. Okinaga T, Mohri I, et al. Induction of hematopoietic prostaglandin D synthase in hyalinated necrotic muscle fibers: its implication in grouped necrosis. Acta Neuropathol 104: 377–384. (2002) *: Equally contributed
  22. Beuckmann CT et al. Cellular localization of lipocalin-type prostaglandin D synthase (beta-trace) in the central nervous system of the adult rat.” J Comp Neurol. 428:62-78. 2000.
  23. Taniike M et al. An apoptotic depletion of oligodendrocytes in the twitcher, a murine model of globoid cell leukodystrophy. J Neuropathol Exp Neurol. 58:644-53. 1999.
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